EFFECT OF SODIUM LAURYL SULFATE (SLS) APPLIED AS A PATCH ON HUMAN SKIN PHYSIOLOGY AND ITS MICROBIOTA


In vivo analysis of CRISPR-edited germinal center murine B cells

The germinal center (GC) reaction is crucial for somatic hypermutation, affinity maturation, and the selection of high-affinity B cells, all of which are hallmarks of the humoral immune response.Understanding the distinct roles of various B cell genes is essential for elucidating the selection mechanisms within the GC reaction.Traditionally, studyi

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Induction of cross-reactive antibodies in mice immunized with conserved influenza A virus neuraminidase-derived linear B-cell epitopes

Introduction.Influenza is a socially significant infection that causes profound damage to populational health and national economy annually.Preventive vaccination is the most effective means to manage influenza and its complications.Diverse influenza vaccines exist, but their common drawback is the narrow specificity, the need for annual renewal of

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